Glimestar-PM1 Tablet ER 10's

• Glimestar-PM1 Tablet ER contains Glimepiride 1mg, Metformin 500mg, Pioglitazone 15mg used to control blood sugar levels in adults with type 2 diabetes mellitus
• It also helps in the proper utilization of insulin by the body
• Addictive drug: No
• Therapeutic Class: Anti Diabetic
• Belongs to Thiazolidinediones class of Anti-diabetic medicines
• Schedule “H” prescription drug Caution: Not to be sold at a retail outlet without the prescription of a registered medical practitioner
• Schedule “G” prescription drug Caution: It is dangerous to take this medication without medical supervision
• Store below 30°C protected from light & moisture
• Keep out of the reach of children

Treatment of Type 2 diabetes mellitus

• It is not safe to consume alcohol while taking Glimestar-PM1 Tablet ER it can cause life-threatening side effects like lactic acidosis
• Do not take a double dose or overdose of Glimestar-PM1 if you miss taking a dose, skip the missed dose and follow your regular schedule as prescribed
   

Glimestar PM1 Tablet may interact with the following medicines, consult your doctor
 

• Antidiabetic drugs (insulin, sitagliptin, empagliflozin)
• Water pills (furosemide), Antithyroid drugs (levothyroxine)
• Anticonvulsant (pregabalin)

Glimestar-PM1 Tablet ER is not safe to take during pregnancy as it may affect the baby. The tablet is safe if properly prescribed only for breastfeeding mothers. The blood sugar level of the baby being breastfed must be monitored when the mother is taking this medication

• Glimepiride helps decrease high blood sugar levels and avoid serious complications of diabetes
• Take it shortly before or with the first main meal of the day. Avoid skipping meals
• Be careful while doing tasks that require focus until you know how Glimepiride affects you
• It can cause hypoglycemia or low blood sugar level when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal
• Always carry some sugary food to take in case you experience symptoms of hypoglycemia such as cold sweats, cool pale skin, tremors, anxiety
• Your doctor must monitor your liver function regularly. Inform your doctor if you develop symptoms, such as Stomach pain, loss of appetite, or jaundice
• Metformin has been prescribed for you, it controls your blood sugar level, and reduces the risk of heart attacks
• Hypoglycemia or low blood sugar level may occur when taken along with other antidiabetic medicines, alcohol, delaying or skipping a meal. Carry a sugar source with you for immediate relief
• Inform your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Metformin may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood
• Prolonged use of Metformin may lead to Vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath, or headache. Notify your doctor if you experience any of these as you may require supplements
• Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication
• Pioglitazone helps to control blood sugar levels
• Full effects may be visible after several weeks of starting Pioglitazone. Keep taking it as prescribed by your doctor
• Monitor your liver enzymes regularly while taking this medicine
• Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling

• Hypoglycemia
• Headache or Dizziness
• Nausea & Vomiting
• Change of Taste
• Diarrhea
• Stomach pain
• Apetite Loss
• Weight gain
• Blurred vision
• Respiratory tract infection
• Numbness
• Bone fracture

Glimestar-PM1 Tablet ER can be taken with food to avoid stomach upset. Swallow the tablet as a whole with a glass of water

Glimestar-PM1 Tablet ER is an antidiabetic medicine that contains Glimepiride 1mg, Metformin 500mg, Pioglitazone 15mg

Glimepiride increases the amount of insulin released by the pancreas to reduce blood glucose

Metformin reduces glucose production in the liver, delays the absorption of sugar in the intestines, increases the body's sensitivity to insulin using it effectively to control blood sugar

Pioglitazone also improves the body’s sensitivity to insulin when Metformin alone is not enough to control blood sugar levels

Q. Does Glimepiride make you sleepy?
Glimepiride does not cause sleepiness but it may cause hypoglycemia when taken with other anti-diabetic medicines which may make you feel sleepy or affect your sleep

Q. Is Glimepiride safe for the kidneys?
Glimepiride does not affect the kidneys of patients with normal kidney function but patients with severe kidney disease must avoid taking it as Glimepiride is eliminated by the kidneys

Q. Does Glimepiride cause memory loss?
No, it is unknown whether Glimepiride causes memory loss but it may cause low blood sugar which affects your concentration and alertness

Q. Who should not take Glimepiride?
Glimepiride should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency, have type 1 diabetes mellitus, or are scheduled to have surgery

Q. How long does it take for Glimepiride to start working?
Glimepiride takes 2 to 3 hours to reduce blood sugar levels continue taking the medication as prescribed by your doctor

Q. How long do I need to take Glimepiride? Can I stop the medication if I feel normal?
Treatment for diabetes is long-term, sometimes lifelong. Glimepiride only controls your sugar levels and does not cure it so do not stop taking the medicine without consulting your doctor

Q. How and when must Glimepiride be taken?
Glimpiride must be taken as advised by your doctor, a single daily dose of Glimepiride is sufficient to control blood sugar levels. It can be taken whole with water before or during breakfast

Q. What happens if I take more than the recommended dose of Glimepiride?
Overdose of Glimepiride may decrease your blood sugar levels and cause hypoglycemia. Severe cases of hypoglycemia with loss of consciousness and coma which requires immediate medical attention and hospital admission

Q. What does Metformin do?
Metformin decreases glucose production from the liver and decreases absorption of glucose in the intestine postmeal while improving the sensitivity of the body towards insulin

Q. Does Metformin cause weight loss?
Yes, Metformin may cause weight loss in people who are overweight or obese, in people who are prone to the risk of diabetes, or in patients who are sensitive or resistant to insulin

Q. What are the benefits of taking Metformin?
Metformin controls your blood sugar levels, promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver, also decreases the amount of sugar absorbed by the intestines

Q. Can Metformin make us sleepy?
Metformin does not cause sleepiness but the use of Metformin may rarely cause sleep disorders and insomnia due to a serious side effect called lactic acidosis, which specifically occurs if your kidneys do not function properly

Q. Can Pioglitazone cause weight gain?
Pioglitazone can cause weight gain due to dosage and fat accumulation but it may be due to water retention in the body in heart failure patients. Heart failure case patients must monitor their weight as it is very important

Q. Can Pioglitazone cause heart failure?
Pioglitazone can cause water or fluid retention that may worsen or speed up heart failure. Pioglitazone taken with insulin can also cause heart failure so consult your doctor if you have any heart disease or diabetes

Q. Can Pioglitazone and Metformin be taken together?
Yes, Pioglitazone can be taken with Metformin by adult patients & obese patients who have type 2 diabetes mellitus when Metformin alone does not manage blood sugar levels

Q. Can Pioglitazone cause bladder cancer?
Pioglitazone can increase the risk of bladder cancer but it happens very rarely. Patients who have or had bladder cancer must not use this medicine, inform your doctor if you see blood in your urine, pain when urinating or a sudden urge to urinate when you take Glimestar-PM1

Q. Does Pioglitazone affect the liver?
Yes, Pioglitazone can cause increased production of liver enzymes. Patients with liver diseases must avoid this medicine

Q. What kind of medicine is Pioglitazone?
Pioglitazone belongs to the thiazolidinediones class of anti-diabetic medicines

• Inform your doctor if you have any kidney, liver, or heart problems before taking this medication
• Patients must consult their doctor if they have bladder cancer, uncontrolled diabetes, lactic acidosis, diabetic ketoacidosis, eye problems caused by diabetes before taking this medicine
• Patients with severe liver or kidney disease must avoid taking this medicine