Adcapone Tablet strip of 10 tablets

Adcapone Tablet is used in the treatment of Parkinson's disease.

Entacapone 200mg

Adcapone Tablet may cause excessive drowsiness with alcohol

Adcapone Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Entacapone : Nausea, Vomiting, Fatigue, Confusion, Constipation, Insomnia (difficulty in sleeping), Nightmare, Hallucination, Increased sweating, Fall, Urine discolouration, Dizziness, Diarrhea, Muscle coordination impaired, Ischemic heart disease, Myocardial infarction, Abdominal pain, Dryness in mouth

Adcapone Tablet may be taken with or without food, but it is better to take it at a fixed time.

Adcapone Tablet is a selective reversible inhibitor which is given in combination with levodopa. It works by inhibiting a chemical messenger [catechol-O-methyl transferase (COMT)] which in turn helps in increasing the amount of dopamine (chemical messenger) in the brain. Thus, an adequate amount of dopamine in the brain helps to coordinate body movements. This is how it works to control symptoms of Parkinson's disease.

Q. Can Adcapone be crushed or split? If not, then how it should be taken?
No, Adcapone should not be crushed or split. Take it as a whole with a full glass of water at the same time as you take a dose of levodopa

Q. Does Adcapone have any effect on urine color?
Yes, Adcapone may cause your urine to change to a brownish-orange color. This effect is common and is not harmful.

Q. Will Adcapone make me sleepy?
The combined use of Adcapone and levodopa has been associated with cases of excessive daytime sleepiness and sudden sleep onset episodes. If you experience these symptoms, then you should neither drive nor operate other complex machinery. Consult your doctor if it becomes troublesome.

Q. What is meant by impulse control disorder caused by Adcapone?
In impulse control disorders, you may get urges or cravings to behave in ways that are unusual for you. In such disorders, you cannot resist the impulse, drive or temptation to carry out certain activities that could harm yourself or others. Additionally, it may include addictive gambling, excessive eating or spending, an abnormally high sex drive or a preoccupation with an increase in sexual thoughts or feelings. In such a case, your doctor may suggest dose reduction or discontinuation of dose.

Q. What if I accidentally take more than the recommended doses of Adcapone?
In case you take more than the recommended doses of Adcapone, you may experience confusion, decreased activity, sleepiness, decreased muscle tone, skin discoloration, and urticaria. If any such symptoms occur, you should seek immediate medical attention in a nearby hospital or contact your doctor.

Q. Does Adcapone cross the blood-brain barrier?
No, Adcapone does not cross the blood-brain barrier. It is useful in prolonging the duration of the benefit obtained from individual doses of levodopa.

Q. Does Adcapone affect fertility?
No, Adcapone does not affect fertility. However, it should be avoided by pregnant and lactating women because there is no sufficient data to support the safety of this patient group.

Q. When should I take entacapone?
Adcapone can be taken anytime but for better response it should be taken around the same time everyday. This also helps you to remember taking it.

Q. What type of drug is Adcapone?
Adcapone belongs to a class of medicines known as COMT (catechol-O-methyltransferase) inhibitors.

Q. Is Adcapone a dopamine agonist?
No, it is not a dopamine agonist. Adcapone is a selective and reversible inhibitor of COMT (catechol-O-methyltransferase) which works by increasing and maintaining sustained levels of levodopa when levodopa is given along with it.

Adcapone Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.