Fructosamine Serum Spectrophotometry Test

Principle: 

• Fructosamine Serum Spectrophotometry Test measures the concentration of fructosamine in the blood
• It utilizes spectrophotometric techniques to assess the absorbance of a complex formed between fructosamine and nitroblue tetrazolium (NBT)
   

Sample Collection:

• A blood sample is collected, typically in a fasting state, to ensure accurate measurement of fructosamine levels
   

Test Procedure:

• The serum is separated from the blood sample
• Fructosamine reacts with NBT, forming a colored complex
• The absorbance of this complex is measured using spectrophotometry
• The concentration of fructosamine is calculated based on the absorbance

• Diabetes Management: Evaluates glycemic control over a shorter duration (2-3 weeks) compared to HbA1c, providing a more immediate assessment
• Monitoring Treatment Efficacy: Helps assess the effectiveness of changes in medication or lifestyle on blood glucose levels

• Fructosamine Levels: Quantification of fructosamine concentration in the serum

• Normal Range: Interpretation of fructosamine levels within the established reference range
• Abnormal Levels: High levels may indicate poor glycemic control, while low levels may suggest rapid changes in glucose levels

• Numeric Value: The test provides a numeric value representing the concentration of fructosamine in the serum
• Reference Range: Results are compared to established reference ranges to determine if values are within normal limits

Q: Why is the Fructosamine test done?
It assesses short-term glycemic control, complementing long-term indicators like HbA1c in managing diabetes
 

Q: How often should this test be done for diabetes monitoring?
Frequency depends on individual health and treatment plans; typically, it may be done every 2-3 weeks
 

Q: Can medications affect Fructosamine levels?
Yes, certain medications may influence results; inform your healthcare provider about all medications
 

Q: What does a high Fructosamine level indicate?
It may suggest poor blood sugar control over the past 2-3 weeks and may prompt adjustments in treatment
 

Q: Can the test be affected by non-diabetic conditions?
Some conditions like liver or kidney disease may impact results; discuss your medical history with your healthcare provider
 

Q: Is fasting necessary before the Fructosamine test?
Typically, fasting is not required, but follow your healthcare provider's instructions for specific test conditions
 

Q: How does Fructosamine testing differ from HbA1c?
Fructosamine reflects short-term glucose control, while HbA1c provides a long-term average; both are valuable in diabetes management